A unique collection of interviews with the CAPICE project scientific supervisors and principal investigators: Prof. Dr. Marcus Munafò, Prof. Dr. Sebastian Lundstrom, Dr. Ralf Kuja-Halkula, Dr. Stephanie van den Berg, Dr. Sarah Bergen, Prof. Meike Bartels, Prof. Christel Middeldorp, Prof. Robert Plomin.
Prof. Dr. Marcus Munafò is a professor of Biological psychology at University of Bristol, UK. He is the principal investigator of two ESRs namely Elis Haan and Laura Schellhas. Two projects are involved at Bristol, both looking at the relationship between maternal health behavior during pregnancy whether the mother smokes or alcohol consumes and relationship between that and mental health of child later in life. These studies try to understand whether there is causal effect of these exposures on offspring psychopathology, and to determine whether DNA Methylation mediates the relationship between exposures in pregnancy and psychiatric outcomes in the offspring.
Prof. Dr. Sebastian Lundstrom is a Psychologist & Assistant professor of genetic epidemiology at University of Gothenburg, Sweden. He is the principal investigator of the ESR namely Sabrina Doering. Their research aims to disentangle the genetic and environmental underpinnings behind the relationship between anxiety and negative life outcomes. Another goal is to try to develop prediction models in order to identify individuals with anxiety/anxiety-symptomatology that have a high likelihood of developing negative life outcomes (for example, mental health problems, poor school achievement, unemployment, sick leave, suicide attempts, and criminality).
Dr. Ralf Kuja-Halkula is a statistician at Karolinska Institutet, Sweden. He is the principal investigator of the ESR namely Ashley Thompson. They work to develop prediction models to identify the individuals with ADHD/ADHD-symptomatology in need for special attention as well as understand the features that characterize the group of individuals with ADHD with the high likelihood of developing negative outcomes.
Dr. Stephanie van den Berg is a Associate professor at University of Twente, The Netherlands. She is the principal investigator of the ESR namely Kratika Agarwal. They work on harmonizing phenotypes by analyzing raw data, it means that there are so many different groups and data sets, trying to bring it into same page regarding what particular trait we are studying in children.
Dr. Sarah Bergen is a Senior researcher at Karolinska Institutet, Sweden. She is the principal investigator of the ESR namely Marica Leone. They investigate interactions between the genetic and environmental factors that influence the development and clinical course of depression.
Prof. Meike Bartels is a professor of Genetics and well-being at VU University Amsterdam, The Netherlands. She is the principal investigator of two ESRs namely Eshim Shahid and Omowonuola Akingbuwa. They mainly focus on genetics of internalizing behavior and attention problems, trying to identify the common genetic variants and genes that influence the development and course of internalizing symptoms across childhood and adolescence.
Prof. Christel Middeldorp is the coordinator of the CAPICE project. In the video below she explains the importance and the goals of the project. We know from large studies that children are experiencing psychiatric symptoms through out their life even in adulthood. CAPICE aims to identify genetic factors that influence this persistent into adulthood and also interplay between genetic and environmental factors. We hope that with this knowledge, we can improve treatments for this children.
Prof. Dr. Robert Plomin is a Professor of Behavioral Genetics at King's College London, UK. He is the principal investigator of the ESR namely Andrea Giuseppe Allegrini. In the video below Professor Robert Plomin talks about the 1st CAPICE Workshop on genetics and developmental psychopathology at King's College London.
